Molecular Sieves
Apexbio Technology LLC SMI-4a 438190-29-5 10mM (in 1mL DMSO)
SMI-4a (CAS 438190-29-5) is a selective inhibitor of the serine/threonine kinase Pim-1 exhibiting an IC50 of 17 nM Pim-1 is implicated in the regulation of cell cycle progression and apoptosis with its overexpression associated with enhanced cell survival in various malignancies SMI-4a demonstrates increased activity compared to related compounds and inhibits downstream mTORC1 signaling and activates AMPK in leukemia cell lines leading to cell cycle arrest and apoptosis induction In preclinical studies SMI-4a reduced tumor volume in xenograft mouse models highlighting its utility for investigating Pim kinase-driven pathways in cancer research
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves, 5 Ã… powder, undried | 69912-79-4 | MFCD00131613 | 500G
Molecular sieves, 5 Ã… powder, undried | 69912-79-4 | MFCD00131613 | 500G
Medchemexpress LLC Semaphorin-4A/SEMA4A 50ug
Recombinant mouse Semaphorin-4A extracellular domain expressed in HEK293 cells, supplied lyophilized with a C-terminal 6xHis tag. Provided at 50 μg with >95% purity and formulated for stability; certificate of analysis and datasheet are available for quality verification.
- Mouse extracellular domain (residues T33-H682).
- Expressed in HEK293 mammalian cells for proper folding and post-translational modifications.
- C-terminal 6xHis tag for affinity purification and detection.
- Lyophilized formulation with stabilizers for extended storage stability.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Supplied at 50 μg suitable for in vitro research applications.
- Certificate of analysis and datasheet provided for quality assurance.
Medchemexpress LLC D-Phenylalanine, N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]- | 1279713-77-7 | 99.5% | 377.82 | 25 MG
CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. It represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β.
- Potent, highly selective TLR3 signaling inhibitor.
- Represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β.
- Shows dose-dependent inhibitory effects blocking Poly (I:C)-induced TLR3 activation with an IC50 of 3.44 μM in RAW 264.7 cells.
- Competes with dsRNA for binding to TLR3 with a Ki of 2.96 μM.
Medchemexpress LLC SMI-4a (TCS-PIM-1-4a) | 438190-29-5 | 99.9% | 273.23 | 1 ML
SMI-4a (TCS-PIM-1-4a) is a potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 μM. It also inhibits Pim-2 (IC50 of 100 μM) but does not significantly inhibit other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity.
- Potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor.
- Inhibits Pim-2.
- Has anticancer activity.
Strem, An Ascensus Company CAS# 70955-01-0. 1kg. Molecular sieves, -600 mesh powder (Linde 4A). MFCD00131613
CAS# 70955-01-0. 1kg. Molecular sieves, -600 mesh powder (Linde 4A). MFCD00131613. Molecular Weight: . Molecular Formula: . Color/form: white pwdr. Strem# 93-5403. http://www.strem.com/catalog/v/93-5403/
FUJIFILM BIOSCIENCES INC ZEOLITE, SYNTHETIC, HS-320 POW
*Orders for this supplier are non-cancellable/non-returnable once they are processed.* Zeolite, Synthetic, HS-320, Powder, Hydrogen Y 25GR
Medchemexpress LLC Dodeca-2E,4E,8Z,10Z/E-N-tetraenoic acid isobutylamide | 866602-52-0 | 98.5% | 247.38 g/mol | C16H25NO | 1mg
Dodeca-2E 4E 8Z 10Z/E-N-tetraenoic acid isobutylamide is a brain-penetrant substance and the main alkamide in Echinacea preparations which might be used for research of common cold and various upper respiratory infections[1]
Medchemexpress LLC 4alpha-phorbol 12-myristate 13-acetate | 63597-44-4 | MFCD00153860 | 99.0% | 616.83 | C36H56O8 | 1 MG
4alpha-phorbol 12-myristate 13-acetate is the inactive stereoisomer of TPA used as a negative control in experiments that monitor TPA-activated signaling events. It is supplied as a high-purity research reagent in a small-mass vial suitable for in vitro assays.
- Inactive negative control for TPA-activated events.
- High purity (99.0%) for reproducible results.
- Molecular formula C36H56O8 and molecular weight 616.83 for accurate identification.
- Supplied in a 1 mg package suitable for small-scale studies.
Strem, An Ascensus Company CAS# 308080-99-1. 250g. Molecular sieves, 1/8'' pellets (Linde 3A). MFCD00131613
CAS# 308080-99-1. 250g. Molecular sieves, 1/8'' pellets (Linde 3A). MFCD00131613. Molecular Weight: . Molecular Formula: . Color/form: off-white pellets Strem# 93-5414. http://www.strem.com/catalog/v/93-5414/
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves 3 A pell1KG
REAGENT Molecular sieves 3 A… pell1KG
Cayman Chemical 15hydroxy ProstaglndIn Dehy
Source: Active recombinant human C-terminal His-tagged 15-PGDH expressed in E. coli • Amino acids: 3-256 • MW: 29.9 kDa