Molecular Sieves
Medchemexpress LLC 4alpha-phorbol 12-myristate 13-acetate | 63597-44-4 | MFCD00153860 | 99.0% | 616.83 | C36H56O8 | 1 MG
4alpha-phorbol 12-myristate 13-acetate is the inactive stereoisomer of TPA used as a negative control in experiments that monitor TPA-activated signaling events. It is supplied as a high-purity research reagent in a small-mass vial suitable for in vitro assays.
- Inactive negative control for TPA-activated events.
- High purity (99.0%) for reproducible results.
- Molecular formula C36H56O8 and molecular weight 616.83 for accurate identification.
- Supplied in a 1 mg package suitable for small-scale studies.
Sigma Aldrich Fine Chemicals Biosciences Molecular sieves 13X powde1KG
MOLECULAR Molecular sieves 13X powde1KG
FUJIFILM BIOSCIENCES INC ZEOLITE SYNTHETIC HS-690 POW
*Orders for this supplier are non-cancellable/non-returnable once they are processed.* Zeolite, Synthetic, HS-690, Powder, Hydrogen Mordenite 25GR
Apexbio Technology LLC TCS-PIM-1-4a 327033-36-3 50mg
TCS-PIM-1-4a is a small-molecule inhibitor targeting Pim kinases a family of serine/threonine kinases It is designed to selectively inhibit Pim kinases thereby modulating signaling pathways related to cell growth and survival TCS-PIM-1-4a exerts its biological activity primarily through activation of AMP-activated protein kinase (AMPK) resulting in inhibition of the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway In cell-based studies TCS-PIM-1-4a demonstrates cytotoxic activity against diverse hematological tumor cell lines including myeloid and lymphoid subtypes with IC50 values ranging from approximately 0 8 to 40 M Based on these pharmacological properties TCS-PIM-1-4a holds research potential in investigations of Pim kinase signaling and therapeutic strategies for hematological malignancies
Medchemexpress LLC Avg-233 | 2151937-80-1 | 98.1% | 100 MG
AVG-233 is a potent, orally active RNA-dependent RNA polymerase (RdRp) inhibitor used for research into respiratory syncytial virus (RSV). It prevents initiation of the viral polymerase complex and shows nanomolar activity against RSV strains and clinical isolates.
- Potent RNA-dependent RNA polymerase inhibitor.
- Reported EC50 = 0.14-0.31 μM against RSV strains and clinical isolates.
- Molecular formula: C26H22ClN5O3.
- Molecular weight: 487.94 g/mol.
- Available as a solid in multiple pack sizes (5 mg-500 mg).
- Intended for research use only; not for human or diagnostic use.
Medchemexpress LLC SMI-4a (TCS-PIM-1-4a) | 438190-29-5 | 99.9% | 273.23 | 1 ML
SMI-4a (TCS-PIM-1-4a) is a potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor with an IC50 of 24 μM and a Ki of 0.6 μM. It also inhibits Pim-2 (IC50 of 100 μM) but does not significantly inhibit other serine/threonine- or tyrosine-kinases. SMI-4a has anticancer activity.
- Potent, selective, cell-permeable, and ATP-competitive Pim-1 inhibitor.
- Inhibits Pim-2.
- Has anticancer activity.
Strem, An Ascensus Company CAS# 69912-79-4. 1kg. Molecular sieves, 1/8'' pellets (Linde 5A). MFCD00131613
CAS# 69912-79-4. 1kg. Molecular sieves, 1/8'' pellets (Linde 5A). MFCD00131613. Molecular Weight: . Molecular Formula: . Color/form: off-white pellets Strem# 93-5410. http://www.strem.com/catalog/v/93-5410/
![Medchemexpress LLC 1H-pyrazolo[4,3-c]pyridine-3,6-dione derivative | 2151937-80-1 | 98.1% | 10MM 1ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000230924.png-250.jpg)
Medchemexpress LLC 1H-pyrazolo[4,3-c]pyridine-3,6-dione derivative | 2151937-80-1 | 98.1% | 10MM 1ML
1H-pyrazolo[4,3-c]pyridine-3,6-dione derivative | 2151937-80-1 | 98.1% | 10MM 1ML
Selleck Chemical LLC SMI-4a
SMI-4a (TCS PIM-1 4a) is a potent inhibitor of Pim1 with IC50 of 17 nM modestly potent to Pim-2 does not significantly inhibit any other serine/threonine- or tyrosine-kinases
Selleck Chemical LLC Dyngo-4a
Dyngo-4a is a potent dynamin inhibitor with IC50 of 0 38 M 1 1 M and 2 3 M for DynI (brain) DynI (rec) and DynII (rec) respectively
Apexbio Technology LLC SMI-4a 438190-29-5 10mM (in 1mL DMSO)
SMI-4a (CAS 438190-29-5) is a selective inhibitor of the serine/threonine kinase Pim-1 exhibiting an IC50 of 17 nM Pim-1 is implicated in the regulation of cell cycle progression and apoptosis with its overexpression associated with enhanced cell survival in various malignancies SMI-4a demonstrates increased activity compared to related compounds and inhibits downstream mTORC1 signaling and activates AMPK in leukemia cell lines leading to cell cycle arrest and apoptosis induction In preclinical studies SMI-4a reduced tumor volume in xenograft mouse models highlighting its utility for investigating Pim kinase-driven pathways in cancer research
Medchemexpress LLC D-Phenylalanine, N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]- | 1279713-77-7 | 99.5% | 377.82 | 25 MG
CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. It represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β.
- Potent, highly selective TLR3 signaling inhibitor.
- Represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β.
- Shows dose-dependent inhibitory effects blocking Poly (I:C)-induced TLR3 activation with an IC50 of 3.44 μM in RAW 264.7 cells.
- Competes with dsRNA for binding to TLR3 with a Ki of 2.96 μM.